Antimicrobial Effectiveness Testing Services

At EMSL Analytical, our comprehensive microbiology laboratory testing services include antimicrobial effectiveness testing (AET) — also known as challenge testing or preservative effectiveness testing. Our AET lab specialists offer challenge testing for a complete range of applications and requirements, including personal care and cosmetic products as well as aqueous pharmaceutical products. Contact us today to get started!

Purposes of Challenge Testing

Antimicrobial effectiveness testing demonstrates the ability of certain compounds to inhibit the growth of microorganisms both in a non-sterile finished product and after a finished product has been opened.

In the case of sterile products (such as those in multi-dose containers), antimicrobial effectiveness tests are used to determine the ability of the formulation to inhibit the growth of microorganisms that may be introduced upon repeated dosage withdrawals.

It is recommended that an AET be used during a stability study of a self-contained product to determine whether the antimicrobial preservative can withstand the shelf life of the product. Antimicrobial effectiveness must be demonstrated in personal care and cosmetic products, as well as aqueous pharmaceutical products such as nasal, ophthalmic, otic, irrigation, oral and dialysis fluids.

EMSL: USP-Compliant Preservative Effectiveness Testing Labs

At EMSL Analytical, we focus on compliance, accuracy and quality control. Our antimicrobial effectiveness tests comply with:

  • US Pharmacopeial Convention (USP) General Chapter 51 for pharmaceutical and medical devices
  • Preservative Test methods published by the Personal Care Products Association (formerly Cosmetic, Toiletries and Fragrance Association)
  • Upon request, tests can be performed to meet European Pharmacopeia requirements

Do you need antimicrobial effectiveness testing for a personal care product, cosmetics product or aqueous pharmaceutical product? Contact EMSL Analytical Labs today to learn more about our challenge testing, stability testing, personal care product testing services and more.

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